Biete - Deuterium » -inning loss on Friday,

ACAPULCO, Mexico -- David Ferrer and Andy Murray, the top two seeded players in the Mexican Open, advanced to the second round on Tuesday while American and third-seeded John Isner became the first major casualty of the tournament, losing 7-6 (4) 7-6 (5) to Croatias Ivo Karlovic. Ferrer, the favourite in Acapulco, had a convincing 6-2, 6-3 victory over Kazakh Mikhail Kukushkin while Murray overcame a sluggish start and claimed a 3-6, 6-1, 6-2 win over Pablo Andujar, from Spain. "I had a difficult start, it was 10 minutes in the match and I was down 5-0, but I started to play more aggressively to get the win and hopefully I can have a good week here", Murray said. "The first set was extremely challenging, he was dictating the points, but later on he was getting tired and put the pressure on him". Murray, who played for the first time ever in Latin America, lost his first three service games and fell into a 5-0 hole, but came back strongly to set up a match against Joao Sousa of Portugal. "I played Joao once in Australia, he was new on the tour then and he has improved. Hes playing good tennis, hes good on clay and on hard courts", added Murray. "He plays similar to Pablo, hopefully I can play aggressively from the start." In the round-of-16, Ferrer, who is trying to win on Mexican soil for the fourth time in his career, will play Spanish compatriot Feliciano Lopez. "I..m not thinking about the final, Im only in the second round", Ferrer said. "Now Im only thinking about playing my best tennis against Feliciano Lopez, he..s a good player I need to give my best to beat him". Ferrer, who now has a 4-0 record against Kukushkin, is coming off an impressive run in the past two weeks of the ATP tour, winning the Buenos Aires tournament and reaching the semifinals in Rio de Janeiro last week. "Playing in Buenos Aires was not in my plans", said Ferrer who replaced his countryman Rafael Nadal in Argentina. "Im tired, but I will not be making any excuses, I need to take a rest now and get well for the rest of the tournament". Earlier, Karlovic served 15 aces to Isner fired eight in a match between two of the games biggest servers. "Im very disappointed," a visibly upset Isner said after the match. "I wanted to do well in here, is a good surface for me, but I played against a guy who played well against me". The 2.11-meter (6-foot-11) Karlovic now has a 3-2 career record against the 2.08-meter (6-foot-10) Isner, whos ranked 13th in the world. Sousa of Portugal came back to defeat Frenchman Adrian Mannarino 1-6, 6-2, 6-2. South Africas Kevin Anderson downed Stephane Robert of France 6-2, 7-6 (7) and will next play Americas Sam Querrey. Also, Alexandr Dolgopolov, from the Ukraine, beat Canadas Vasek Pospisil 6-2, 6-2 and seventh-seeded Ernests Gulbis had a 6-1, 6-1 victory over Taiwans Yen-Hsun Lu. Latvias Gulbis won his fifth career title last week in Marsella. On the womens side of the combined ATP-WTA tournament, top-seeded Dominika Cibulkova had a 6-3, 6-4 win over Urszula Radwanska, from Poland, Eugenie Bouchard eliminated Shahar Peer from Israel 6-2, 6-2, American Victoria Duval had a 6-2, 6-4 win over Czech Iveta Melzer and Estonian Kai Kanepi prevailed 6-1, 3-6, 6-2 against Jana Cepelova, from Slovakia. DaQuan Jones Jersey . The question all fans want to know heading into this light heavyweight affair is will Rua display his true potential. 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The Toronto Blue Jays had both a five-game overall win streak and a nice run of success at Fenway Park end in an extra-inning loss on Friday, but theyll try to get both re-started on Saturday night when they visit the Boston Red Sox for game two of a three-game series. Toronto had won six in a row in Boston before the 9-8 defeat in which they led by two runs heading into the bottom of the 10th inning before closer Casey Janssen managed only one out while allowing three runs. One game earlier, the Red Sox had lost a ninth-inning lead to the New York Yankees. "You score those two runs in the top of the 10th there, so youre feeling really good and then bam, bam, bam, bam," Toronto manager John Gibbons said. "Nine times out of 10 we win that game." Another loss came in the form of Melky Cabrera, who broke his right pinky finger and will miss the rest of the season. He was leading the team with a .301 batting average. Boston has lost nine of 11 home starts by Saturdays pitcher, Clay Buchholz, whos won two of eight decisions at Fenway with a 7.20 earned run average. Toronto has homered 13 times at Fenway this season. Buchholz is 0-4 in his last six home meetinggs with Toronto, including two losses this season in which hes compiled a 10.dddddddddddd4 ERA. The right-hander won for the first time in eight starts in his last outing, defeating Tampa Bay, 3-0, with a complete-game three-hitter. Yoenis Cespedes, who arrived via deadline trade with Oakland, had four hits in Fridays win and is hitting .392 in his last 12. "Hes proven to us time and time again in RBI situations, hes got a knack for it," Boston manager John Farrell said. "Hes aggressive, hes strong and hes got all-field coverage." The Blue Jays start lefty J.A. Happ, whos beaten Boston twice this season with a 2.71 ERA in three starts. Cespedes has two hits against him in 10 career at-bats. Happ had dropped three decisions in his last six starts before defeating the Yankees, 4-3, on Sunday with seven innings of work. On Friday, Cespedes hit to center with the bases loaded in the bottom of the 10th capped a rally. Xander Bogaerts collected three hits and drove in two, Mookie Betts added two hits, an RBI and scored three times, while Mike Napoli drove in a run and scored once. Edwin Encarnacion and Jose Bautista each hit a two-run homer for the Blue Jays. 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